Brightfield microscopy has been widely used for hundreds of years, while reflection contrast microscopy is relatively new technology. As one of the earliest and simplest microscopy techniques, ...

THE detail seen in a highly magnified electron micrograph is to-day limited more by a lack of contrast in the image than by any lack of resolution in the microscope, which is now usually capable of ...

This article describes a new method (VS-FPM) for analysis of unstained tissues based on the application of supervised machine learning to generate brightfield hematoxylin and eosin (H&E) images from ...

This seminar provides an overview of fluorescence microscopy in cancer research and other cell-based applications in the biosciences discovery workflow. In comparison with phase contrast and ...

Transmission Electron Microscopes can be used for a variety of different techniques, which set them apart from other forms of microscope. The first is metal shadowing or negative staining. TEM ...

Typically, when diagnosing a skin tumor, a biopsy is needed to extract tissue that is later sectioned into thin layers, stained, and examined under a microscope for abnormalities in a process called ...

Sensing: point-of-care sensors, mobile-phone enabled sensors, field-based sensing and measurement systems with applications in mobile health and telemedicine, environmental monitoring (for example, ...

Non-invasive skin diagnosis: A trained deep neural network transforms reflectance confocal microscopy images of unstained intact skin into corresponding virtually stained tissue images. (Courtesy: ...

Traditional invasive biopsy followed by histological staining remains the benchmark for diagnosis of skin tumors, but photonics-based alternatives could offer several advantages. Progress towards ...

Gram staining is a type of differential staining used to distinguish between Gram positive and Gram negative bacterial groups, based on inherent differences in their cell wall constituents. Stains ...

Rebecca Bonfig and Matthew Weitzman (both Olympus Life Science, MA, USA) explore the ways researchers can make the most out of their treasured neural and brain tissue samples using three different ...