PER-seq could be easily adapted to investigate how deoxynucleotide triphosphate concentration and stoichiometry affects the type and frequency of replication errors. Measuring repair efficiency and ...
C-to-T transitions in CpG dinucleotides are the most prevalent mutations in human cancers and genetic diseases. These mutations have been attributed to deamination of 5-methylcytosine (5mC), an ...
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