Targeting epigenetic modifiers and splicing regulators together may offer new acute myeloid leukemia treatment paths

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...
Nature

Splice Site Prediction Using Machine Learning Techniques

Splice site prediction using machine learning techniques is a rapidly advancing field that integrates computational innovation with genomics. By harnessing methods such as deep learning, graph ...
insideHPC

Splice Machine’s New Open-Source RDBMS Sandbox Goes Live on AWS

Splice Machine, the open-source RDBMS powered by Hadoop and Spark, announced a cloud-based sandbox for developers to put its new open-source 2.0 Community Edition to the test. In addition, the Company ...
Technology Networks

RNA Splicing Errors Disrupt Cellular Identity in Acute Myeloid Leukemia

New research provides a mechanistic map of how genetic mutations disrupt RNA splicing in acute myeloid leukemia.
AZoLifeSciences on MSN

Dual genetic mutations drive RNA mis-splicing and leukemia progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...
GEN

RNA Splicing Visualized, Easing the Design of Small-Molecule Modulators

The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...