A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications.

For patients with chronic viral hepatitis, clinicians instinctively rely on liver enzyme measurements to estimate disease activity and assess need for liver biopsy or antiviral treatment. Although ...

Halogenated compounds are widespread in the pharmaceutical and agrochemical industries. But the reagents used to make them can produce hazardous waste and mixtures of compounds. Enzymes can provide a ...

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, ...

To be used industrially, enzymes usually need to undergo some surgery before they can become chemical workhorses. It may take a nip here, or a tuck there, to sculpt their active site into a shape that ...

Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme ...

A better strategy for developing more effective cholesterol-lowering drugs may come from the first studies of the structural mechanism by which the widely prescribed statin drugs, such as Lipitor and ...

Liver enzymes can fluctuate due to factors like hormonal changes or reactions to medications. Fluctuations are often temporary, but long-term changes may indicate a condition that requires medical ...

Urbana –University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future ...