(Volodymyr Yakimchuk/Creatas Video+/Getty Images Plus) A seismic shift in the selection pressures acting on humans may have ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Somewhere between 2% and 19% of the genetic ancestry carried by present-day West African populations traces back to an ...

Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful of people. Building upon its success, the 1000 Genomes Project was ...

Researchers have put together the most complete view yet of the genetic variation in humans, presented in two studies in the journal Nature. In a social media landscape shaped by hashtags, algorithms, ...

For more than a century, human origins have been told as a story of expansion, migration, and survival. But deep in that ...

Ancient encounters between humans and the mysterious Denisovans are still shaping people today. By analyzing genomes from populations across the Pacific, researchers uncovered evidence that the ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

Our understanding of human metabolism is mostly based on dedicated hypothesis testing in experimental settings, informed by model organisms or observations in patients with rare diseases. Only ...