The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens.

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...

The latticework of extracellular protein that surrounds brain cells forms a particularly dense mesh around fast-spiking interneurons. Why do these cells need such thick coats? In the July 17 Nature ...

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

Balanced synaptic inhibition, controlled by multiple synaptic adhesion proteins, is critical for proper brain function. MDGA1 (meprin, A-5 protein, and receptor protein-tyrosine phosphatase mu [MAM] ...

A researcher at the University of Basel, in collaboration with a colleague in Austria, has developed a new model that provides a holistic view on how our brain manages to learn quickly and forms ...

Spinogenix, the company behind the once-a-day pill that restored lost nerve cell connections in people with amyotrophic lateral sclerosis (ALS), has now set its sights on using the pill to provide a ...

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...