Mast cells are centrally implicated in the progression of diabetic kidney disease through their roles in inflammation, fibrotic remodelling and microvascular dysfunction. In the diabetic milieu, ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Mast cells are central effectors in asthma, acting as both initiators and amplifiers of airway inflammation. Residing in peribronchial tissues and the epithelium, they respond to immunoglobulin E (IgE ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect against ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

Almost all animal species—including humans—have blood cells, but between different species our blood tells different stories.

Systemic mastocytosis (SM) is a rare blood disorder in which the body produces too many mast cells. Part of the immune response, mast cells are a type of white blood cell that releases histamine in ...