PROVIDENCE, R.I. [Brown University] — Neuroscientists are eagerly, but not always successfully, looking for proof that optogenetics – a celebrated technique that uses pulses of visible light to ...
University of Rochester researchers have demonstrated a noninvasive method using BL-OG, or bioluminescent optogenetics, that harnesses light to activate neurons in the brain. The ability to regulate ...
Optogenetics refers to the expression of light-sensitive proteins in defined cell populations, allowing the use of light to manipulate cellular physiology. Optogenetic tools have opened up entirely ...
Their proposed mapping strategies, outlined in two Nature Neuroscience papers, combine holographic optogenetics, a method to selectively and precisely stimulate or silence specific neuron populations, ...
To understand and manipulate components of the brain, “the central challenge in neuroscience is the difficulty of controlling just one type of neuron at a time!” observed Francis Crick prophetically ...
They look like storm clouds that could fit on the head of a pin: Organoids are three-dimensional cell cultures that play a key role in medical and clinical research. This is thanks to their ability to ...
Intercellular electrical coupling is an essential means of communication between cells. It is important to obtain quantitative knowledge of such coupling between cardiomyocytes and non-excitable cells ...
A minimally invasive optogenetic technique that does not require brain implants successfully manipulated the activity of neurons in mice and monkeys, researchers report April 29th in the journal ...
A new state-of-the-art brain imaging technique could, someday, make fMRI neuroimaging technology and current optogenetic methods seem antiquated. This week, a team of Caltech researchers from the ...
It is almost ten years since the scientific journal Science called optogenetics the "breakthrough of the decade". Put simply, the technique makes it possible to control the electrical activity of ...
Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated ...
A minimally invasive optogenetic technique that does not require brain implants successfully manipulated the activity of neurons in mice and monkeys, researchers report. The researchers first ...