Inducible promoters provide remarkable utility when sustained transgene expression compromises plant development or agronomic performance.

A research group at the Stowers Institute for Medical Research says it has put to rest the notion that a gene promoter is only a promoter. They report, in the current issue of eLife Sciences, that ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which ...

In this study, researchers analyzed large ASD whole genome sequencing data and found that promoter de novo mutations in TADs containing ASD genes were specifically associated with the disease.