Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...
Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...
Boosting the cell's own cleanup: New class of small molecules accelerate natural protein degradation
Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
Silent cells deep in your spinal cord may hold a surprising key to healing after devastating injuries and brain disease. A ...
A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...
A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...
The startup is developing a medicine that can very specifically degrade cancerous forms of EGFR, the target of an array of ...
Researchers create Disobind, an AI tool predicting protein interactions, advancing disease biology and drug design applications.
When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and ...
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