PicoGreen dsDNA quantitation reagent is used to quantitate double-stranded DNA and is a highly sensitive fluorescent nucleic acid stain. PicroGreen is used in a wide range of molecular biological ...

With the advent of new technologies that aim to more clearly discern subtle and complex information from small samples, the requirement for setting quality control processes has never been greater.

HPLC has long been regarded as the standard for antibody quantitation. It is extensively used in drug development processes to quantitate antibodies in cell culture supernatants, fed-batch flasks, and ...

Mass spectrometry (MS) users need software solutions that make it easier to work with complex data while ensuring accurate peak integration and quantitation. Often this comes with limitations around ...

Different methods give different answers when calculating limits for impurities. The prediction interval method may be the best option. Regulations require drug manufacturers determine the detection ...

To verify these requirements, the cleaning itself must be evaluated, and the analytical instruments typically used for cleaning validation are the ultraviolet-visible spectrophotometer, the total ...

Metabolomics research involves two approaches: untargeted analysis, which provides a broad overview of molecular changes but lacks precision, and targeted analysis, which focuses on specific ...

Biomarker quantitation in laser microdissected brain tissue is limited by minimal sample volumes and low analyte concentrations. Conventional LC-MS/MS methods require larger tissue samples, ...

In this presentation, we will cover the accurate determination and quantitation of nitrosamine impurities and NDSRIs in drug substances and products using LC-MS/MS based analytical strategies that can ...