(A) Schematic of the experimental design and analysis. Paracancerous and cancer tissues obtained from surgically resected DLBCLs were split and processed for scRNA-seq and spatial transcriptomics. (B) ...

Enables Whole-Transcriptome In Situ Spatial Biology with Single-Cell Sensitivity at Scale. Debuts at AACR Annual Meeting 2026 ...

In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment by analyzing over one hundred tumor sections across six types of ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an unprecedentedly detailed view of healthy human skin, revealing cellular ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Lucy Shapiro received this year’s Lasker Special Achievement Award for her discovery of how bacteria use genetic circuits to encode three-dimensional cellular life. “I was quite shocked, truly,” said ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...