Synaptic plasticity, the ability of synapses to strengthen or weaken over time in response to changes in their activity, is a central foundation of learning and memory. At synapses, presynaptic cells ...

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature. These new findings, published in ...

Researchers at Northwestern University have identified a specific step inside brain synapses where the toxic Alzheimer’s ...

For all its mysteries, the brain can sometimes be described through simple metaphors. For example, communication between neurons works in many ways like a busy shipping depot: components come in, ...

Prevailing hypotheses on the mechanisms of antidepressant action posit that antidepressants directly counteract deficiencies in major neurotransmitter signaling systems that underlie depression. The ...

For several decades, the glutamate delta-1 receptor (GluD1) has remained an enigmatic entity among ionotropic glutamate receptors (iGluRs), primarily due to its lack of classical ion channel activity.

Bioengineers and neuroscientists at the Wu Tsai Neurosciences Institute at Stanford University have developed a highly sensitive tool for detecting brain cells' subtlest electrical signals. Published ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

While the role of barrier function in establishing a protective, nutrient-rich, and ionically balanced environment for neurons has been appreciated for some time, little is known about how signaling ...

Researchers at Indiana University have identified a single enzyme in brain neurons that, when removed, sharply reduced the ...

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...