Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

A protein that helps cancer cells hide from the immune system may have a critical weakness, according to research that could ...

Using a variety of laboratory and animal models, the team found that cysteine fuels the production of the antioxidant glutathione to regulate T-cell activity, but it also helps T cells multiply and ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Physical exercise may help reduce inflammation in MS by changing immune activity, a study in mice and patients suggests.

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...

Fortitude Biomedicines, Inc., (Fortitude) a leading biopharmaceutical company focused on immune cell targeting biologics and molecular glue payload–enabled antibody–drug conjugates (ADCs) for the ...