The thymus prevents autoimmunity by inducing apoptosis of the T cells that express autoreactive receptors to self peptides. But this mechanism alone is insufficient and CD4+CD25+ regulatory T cells ...

Find out about TECregen's, a Basel-based company developing novel biologics designed to rejuvenate the thymus, “thymopoietics ...

The thymus is a specialised primary lymphoid organ that underpins the development and education of T cells. Here, immature progenitors undergo a tightly regulated series of events that not only ...

A recent study in Nature Immunology by Dr. Alfred Singer and colleagues demonstrate how T cells develop through a complex process known as agonist signaling. This novel study helps establish ...

Researchers from UC Riverside School of Medicine collaborated with researchers at the Weizmann Institute of Science in Israel and uncovered a new type of cell in the thymus which is responsible for ...

Tolerance Bio’s Implanted iPSC-derived Thymic Organoids Enable In Vivo Positive Selection of Human T cells and Tumor Burden Reduction in Melanoma Patient-specific human immune system-bearing mouse ...

Early thymic progenitor (ETP) cells, derived from hematopoietic stem cells in the bone marrow, enter the thymus at the cortical-medullary junction (CMJ), retaining multipotent differentiation ...

Early thymic progenitor (ETP) cells, derived from hematopoietic stem cells in the bone marrow, enter the thymus at the cortical-medullary junction (CMJ), retaining multipotent differentiation ...