Salt-inducible kinase 2 (SIK2) is a serine/threonine kinase that regulates transcriptional programs in myeloid cells by phosphorylating transcriptional coregulators. In macrophages, SIK2 promotes the ...

Ulcerative colitis is a condition that affects your colon and rectum. Its symptoms vary based on how severe it is. They can range from mild cases with a few stomach cramps and constipation, to more ...

Unfortunately the cause of ulcerative colitis is unknown, although both genetic and the environmental causes have been proposed. Most patients with ulcerative colitis do not have anyone else in the ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...

EQ504 is an oral, selective aryl hydrocarbon receptor (AhR) modulator with colon-specific delivery that Equillium says is differentiated by targeting immune modulation, barrier function, and mucosal ...

Your belly hurts. The diarrhea keeps coming. And you certainly don’t feel like eating. These can be telltale signs of colitis. But which kind? Colitis is a term used to describe inflammation in your ...

Next up video playing in 10 seconds Which Tests Check for Ulcerative Colitis Remission? Alan Moss, MD, chief scientific officer of the Crohns & Colitis Foundation, defines the typ ...