The injury bug has bitten and many teams have been eliminated from playoff contention but the games go on, and there are some critical matchups in Week 16 of the 2025 NFL season. One of the biggest games is Bears vs.

Potential fantasy impacts: Both teams are used to playing in the cold, so don't sweat that impact. The wild card, here, may be the winds. Then again, both Caleb Williams and Jordan Love have strong arms, so they may still let it rip on long passes. So, the only tricky play may be each kicker, having to negotiate the winds.

Rivers' comeback is a feel-good story, but is it good for the Colts? Meanwhile, we like the Seahawks and Bears in tight divisional games.

Will DK Metcalf continue his recent hot streak? Can Emeka Egbuka get back on track? Check out all of Michael Florio's WR starts and sits for Week 16 of the 2025 NFL fantasy season.

Jamey Eisenberg breaks down which RBs you want to leave on your benches and others you should be starting in Week 16.

Jameson Williams readies for shootout conditions with the Steelers, Mike Evans continues to pick up where he left off, and Tee Higgins and Drake London hope to return from injury.

Is Bucky Irving poised to bounce back from a disappointing outing? Which rookie running back should be in your lineup? Check out all of Michael Florio's RB starts and sits for Week 16 of the 2025 NFL fantasy season.

The Lineup Cheat Sheet was created so that you could get quick answers to your Fantasy start/sit questions with the analysis already built in. For detailed rationale, check out my latest content, including my weekly Lineup Decisions column.