Researchers have located a previously unknown function in the so-called histones, which allows for an improved understanding of how cells protect and repair DNA damages. This knowledge may eventually ...
Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly burly of chemical exchanges are ones that attach small ...
UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around. The researchers discovered ...
Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...
In our cells, 6 feet (1.8 m) of DNA gets crammed into chromosomes that fit inside a 6-µm-wide nucleus. The proteins that help pack up that genetic material are histones, which act as spools around ...
The upper right portion illustrates viral nucleosome-like particles formed by co-occurring viral histone triplets and singlets. On the lower right, a network depicts distinct types of viral ...
Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...
Chromatin integrity and functionality is governed by the controlled assembly and disassembly of nucleosomes. An elaborate histone chaperone network governs histone provision, chromatin assembly, ...
The linker histones, H1 and its variant forms, have been implicated in the formation of higher orders of chromatin structure and gene repression. Three recent manuscripts have reexamined the location ...
This article was originally featured on Knowable Magazine. Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly ...