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Linzess for IBS-C: What You Should Know Linzess (linaclotide) is a prescription medication often used to help manage Irritable Bowel Syndrome with Constipation (IBS-C). IBS-C is a type of IBS where the main symptoms are abdominal pain, bloating, and infrequent, difficult-to-pass stools. Unlike over-the-counter laxatives, Linzess works by increasing fluid in the intestines and speeding up how quickly stool moves through the gut. This can help reduce constipation and improve overall gut motility,
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